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Many therapeutic agents can be used for the pharmacologic management of hypertension.
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure).^[1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke andmyocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease.^[2] There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazidediuretics, calcium channel blockers

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Eptus (Eplerenone) is primarily used to help prevent congestive heart failure following a heart attack. It may also be used to treat hypertension (high blood pressure).

Eplerenone belongs to a class of drugs called aldosterone antagonists or mineralocorticoid receptor antagonists. It blocks the biological effect of aldosterone, a naturally released hormone that raises blood pressure by acting on aldosterone/mineralocorticoid receptors.